Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men’s body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.
Inclusion
Brand new prevalence regarding sterility certainly one of lovers away from reproductive age ranges, considering various sources, from 8% to twenty-five% [1–3]. Men infertility ‘s the just factor in infertility during the 20–30% from cases and one thing causing sterility when you look at the 50% of all of the sterility instances . New comparison off male fertility always includes medical examination and you will comparison into site values of the adopting the semen details: frequency, full sperm count, amount, motility and you will morphology (Dining table 1) . Reasonable sperm fertility and you may/otherwise top quality can be obtained inside 90% of lovers which have fertility problems . Regarding comparison of fertility, the fresh levels off male reproductive hormones are also reviewed. Now, the molecular constitution out-of spunk muscle, examined by the contrasting the amount of DNA fragmentation or oxidative worry could have been increasingly considered. Several knowledge utilize the DNA fragmentation list (DFI) as the an indicator of being pregnant achievements. Considering Evenson and you can Wixon, DFI selections away from three to five% in the healthy boys, while you are a good DFI out-of ? 30% was of this shorter fertility . Currently outlined genetic points, along with each other chromosomal aberrations and you may monogenic alter, account for no more than ten–15% out of cases of male infertility . The reason for fertility problems could be ecological things. The goal of the analysis would be to get acquainted with the connection ranging from diet, time balance and fertility costs inside the males.
Means from books search
A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’ escort service Downey, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.
| Semen factor | Site maximum (95% depend on times) |
|---|---|
| Sperm volume | step one.5 ml (step one.4–1.7) |
| Complete sperm count | 39 million for each and every ejaculate (33–46) |
| Spunk focus | 15 mil for each and every ml (12–16) |
| Efforts | 58% alive (55–63) |
| Modern motility | 32% (31–34) |
| Full (modern + nonprogressive) motility | 40% (38–42) |
| Morphologically typical forms | 4.0% (step three.0–cuatro.0) |